WegovyRx
GLP-1 weekly injection
semaglutideConfirmed at visit
Rx · prescription required
GIP + GLP-1 weekly injection
Zepbound®
tirzepatide · Weekly injection (single-dose vial or KwikPen)
A once-weekly injection that acts on two appetite and blood-sugar hormones, GIP and GLP-1. In a head-to-head trial it produced more weight loss than semaglutide.
From $299/mo
From $299/mo at 2.5 mg. Higher strengths cost more. No membership or visit fees. Full refund if you aren't approved.Drug classDual GIP and GLP-1 receptor agonist
Filled throughLicensed U.S. partner pharmacy
Starting dose2.5 mg once weekly
Available strengths
2.5 mg5 mg7.5 mg10 mg12.5 mg15 mg
How it works
Tirzepatide mimics two gut hormones that signal fullness and help regulate blood sugar. Most people notice smaller portions and fewer cravings as the dose steps up.
How dosing works
Increase in 2.5 mg steps after at least 4 weeks on the current dose. Maintenance is 5, 10 or 15 mg weekly. Your clinician sets the pace based on how you feel and adjusts it through your portal.
Who shouldn't take it
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Serious hypersensitivity to tirzepatide
Your intake screens for these before a clinician reviews your chart.
Important safety information
Boxed warningRisk of thyroid C-cell tumors. Tell your clinician about any lump or swelling in your neck, trouble swallowing, hoarseness or shortness of breath.
Do not use if you have
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Serious hypersensitivity to tirzepatide
Serious risks
- Pancreatitis: stop and get care for severe stomach pain that won't go away
- Gallbladder problems, including gallstones
- Low blood sugar, especially with insulin or a sulfonylurea
- Kidney problems from dehydration after vomiting or diarrhea
- Serious allergic reactions
- Changes in vision in people with type 2 diabetes
- Depression or thoughts of suicide: tell your clinician about mood changes
- Risk of breathing food or liquid into the lungs during anesthesia or sedation
Common side effects
- Nausea, vomiting, diarrhea or constipation
- Stomach pain, indigestion or bloating
- Fatigue, headache or dizziness
- Injection-site reactions (injectables)
Also know
Birth control pills may work less well for 4 weeks after starting and after each dose increase. Use a backup or non-oral method.
Pregnancy
Tell your clinician if you are pregnant, planning to become pregnant or breastfeeding. Weight-loss medicines are not used during pregnancy.
This is not the full safety information. Read the full prescribing information and talk with your clinician.
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